Biography

Dr. Miller is a Professor in the division of pediatric endocrinology. She graduated with her M.D. from the University of Florida in 1998, and her M.S. in Clinical Investigation from the University of Florida in 2005. She has done all of her training in pediatrics and pediatric endocrinology at the University of Florida. She specializes in the care and treatment of individuals with Prader-Willi syndrome and other genetic causes of early-onset excessive weight gain.

Education

Master of Clinical Investigation
University of Florida
2003-2005

Pediatric Endocrinology Fellowship
University of Florida
2001-2004

Pediatric Residency
University of Florida
1998-2001

Medical Doctor
University of Florida
1994-1998

Master of Science
Emory University
1990-1994

Bachelor of Science
Emory University
1990-1994

Board Certifications

Pediatric Endocrinology

Honors and Awards

Castle Connolly Regional Top Doctors
peer nomination – extensive research and careful review and screening by our doctor-directed research team
2018

Customeer Service Key Award
Shands Hospital
2017

Customer Service Key Award
Shands Hospital
2016

Patient’s Choice Award
National Award
2014-2018

Compassionate Doctor Award
National Award
2011-2018

Research Interests

My research focuses on investigation of the etiology and possible treatment for obesity and metabolic abnormalities in individuals with Prader-Willi syndrome and early-onset obesity. I have been working towards achieving an appropriate treatment for hyperphagia for the past 12 years. I currently follow over 500 patients with Prader-Willi syndrome from around the world, and over 100 patients with early-onset obesity due to other genetic causes. I am working on clinical treatment trials to treat hyperphagia in individuals with Prader-Willi syndrome and early-onset obesity.

Publications

Influence of Molecular Classes and Growth Hormone Treatment on Growth and Dysmorphology in Prader-Willi Syndrome: A Multicenter Study
Clinical Genetics
2021

Adults with Prader-Willi syndrome exhibit a unique microbiota profile.
BMC research notes
2021

Microbiota profile and efficacy of probiotic supplementation on laxation in adults affected by Prader-Willi Syndrome: A randomized, double-blind, crossover trial.
Molecular genetics & genomic medicine
2020

Dietary Management for Adolescents with Prader-Willi Syndrome.
Adolescent health, medicine and therapeutics
2020

Prader-Willi Syndrome – Clinical Genetics, Diagnosis and Treatment Approaches: An Update.
Current pediatric reviews
2019

Molecular genetic classification in Prader-Willi syndrome: a multisite cohort study.
Journal of medical genetics
2019

Early Diagnosis in Prader-Willi Syndrome Reduces Obesity and Associated Co-Morbidities.
Genes
2019

Birth seasonality studies in a large Prader-Willi syndrome cohort.
American journal of medical genetics. Part A
2019

A multidisciplinary approach to the clinical management of Prader-Willi syndrome.
Molecular genetics & genomic medicine
2019

The effects of Bifidobacterium animalis ssp. lactis B94 on gastrointestinal wellness in adults with Prader-Willi syndrome: study protocol for a randomized controlled trial.
Trials
2018

Oxytocin and Naltrexone Successfully Treat Hypothalamic Obesity in a Boy Post-Craniopharyngioma Resection.
The Journal of clinical endocrinology and metabolism
2018

Multicentre study of maternal and neonatal outcomes in individuals with Prader-Willi syndrome.
Journal of medical genetics
2018

Hormonal, metabolic and skeletal phenotype of Schaaf-Yang syndrome: a comparison to Prader-Willi syndrome.
Journal of medical genetics
2018

Oxytocin treatment in children with Prader-Willi syndrome: A double-blind, placebo-controlled, crossover study.
American journal of medical genetics. Part A
2017

The High Direct Medical Costs of Prader-Willi Syndrome.
The Journal of pediatrics
2016

Higher plasma orexin a levels in children with Prader-Willi syndrome compared with healthy unrelated sibling controls.
American journal of medical genetics. Part A
2016

Higher plasma orexin A levels in children with Prader-Willi syndrome compared with healthy unrelated sibling controls.
American journal of medical genetics. Part A
2016

Growth Charts for Prader-Willi Syndrome During Growth Hormone Treatment.
Clinical pediatrics
2016

Elevated plasma oxytocin levels in children with Prader-Willi syndrome compared with healthy unrelated siblings.
American journal of medical genetics. Part A
2016

The neurobiological drive for overeating implicated in Prader-Willi syndrome.
Brain research
2015

Medication Trials for Hyperphagia and Food-Related Behaviors in Prader-Willi Syndrome.
Diseases (Basel, Switzerland)
2015

Laparoscopic sleeve gastrectomy in 108 obese children and adolescents ages 5 to 21 years by Alqahtani AR, Antonisamy B, Alamri H, Elahmedi M, Zimmerman VA.
Annals of surgery
2015

Hyperghrelinemia in Prader-Willi syndrome begins in early infancy long before the onset of hyperphagia.
American journal of medical genetics. Part A
2015

Growth charts for non-growth hormone treated Prader-Willi syndrome.
Pediatrics
2015

Perioperative outcomes of pancreaticoduodenectomy compared to total pancreatectomy for neoplasia.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
2014

Morbidity of total pancreatectomy with islet cell auto-transplantation compared to total pancreatectomy alone.
HPB : the official journal of the International Hepato Pancreato Biliary Association
2014

Hypoglycemia in Prader-Willi syndrome.
American journal of medical genetics. Part A
2014

Frequency of Prader-Willi syndrome in births conceived via assisted reproductive technology.
Genetics in medicine : official journal of the American College of Medical Genetics
2014

Effects of metformin in children and adolescents with Prader-Willi syndrome and early-onset morbid obesity: a pilot study.
Journal of pediatric endocrinology & metabolism : JPEM
2014

An open-label pilot study of N-acetylcysteine for skin-picking in Prader-Willi syndrome.
American journal of medical genetics. Part A
2014

Prader-Willi Syndrome and Sleep-Disordered Breathing
Pediatric Annals
2013

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features.
The Journal of clinical investigation
2013

Altered functional brain networks in Prader-Willi syndrome.
NMR in biomedicine
2013

Unique and atypical deletions in Prader-Willi syndrome reveal distinct phenotypes.
European journal of human genetics : EJHG
2012

Prader-Willi syndrome.
Genetics in medicine : official journal of the American College of Medical Genetics
2012

Letter to the editor: Long-term experience with duodenal switch in adolescents.
Obesity surgery
2012

Approach to the child with prader-willi syndrome.
The Journal of clinical endocrinology and metabolism
2012

Nutritional phases in Prader-Willi syndrome.
American journal of medical genetics. Part A
2011

Carnitine and coenzyme Q10 levels in individuals with Prader-Willi syndrome.
American journal of medical genetics. Part A
2011

Sleep disordered breathing in infants with Prader-Willi syndrome during the first 6 weeks of growth hormone therapy: a pilot study.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
2009

Sleep disordered breathing in infants with Prader-Willi syndrome during the first 6 weeks of growth hormone therapy: a pilot study.
Journal of Clinical Sleep Medicine
2009

Early childhood obesity is associated with compromised cerebellar development.
Developmental neuropsychology
2009

“Efficacy of laparoscopic sleeve gastrectomy as a stand-alone technique for children with morbid obesity” and “BioEnterics intragastric balloon for treatment of morbid obesity in Prader-Willi syndrome: specific risks and benefits”.
Obesity surgery
2009

Potency and fate specification in CNS stem cell populations in vitro.
Cell stem cell
2008

Pituitary abnormalities in Prader-Willi syndrome and early onset morbid obesity.
American journal of medical genetics. Part A
2008

Sylvian fissure morphology in Prader-Willi syndrome and early-onset morbid obesity.
Genetics in medicine : official journal of the American College of Medical Genetics
2007

Management approaches for pediatric obesity.
Nature clinical practice. Endocrinology & metabolism
2007

Intracranial abnormalities detected by three-dimensional magnetic resonance imaging in Prader-Willi syndrome.
American journal of medical genetics. Part A
2007

Enhanced activation of reward mediating prefrontal regions in response to food stimuli in Prader-Willi syndrome.
Journal of neurology, neurosurgery, and psychiatry
2007

The treatment of type 2 diabetes mellitus in youth : which therapies?
Treatments in endocrinology
2006

Short-term effects of growth hormone on sleep abnormalities in Prader-Willi syndrome.
The Journal of clinical endocrinology and metabolism
2006

Central hypothyroidism with oxcarbazepine therapy.
Pediatric neurology
2006

The management of type 2 diabetes mellitus in children and adolescents.
Journal of pediatric endocrinology & metabolism : JPEM
2005

Source: University of Florida Health